• Composition of gut microbiota of children and adolescents with perinatal HIV infection taking antiretroviral therapy in Zimbabwe 

      Flygel, Trym Thune; Sovershaeva, Evgeniya; Classen-Weitz, Shantelle; Hjerde, Erik; Mwaikono, Kilaza S.; Odland, Jon Øyvind; Ferrand, Rashida A.; McHugh, Grace; Gutteberg, Tore Jarl; Nicol, Mark P.; Cavanagh, Jorunn Pauline; Flægstad, Trond (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-24)
      <p><i>Background - </i>Human immunodeficiency virus (HIV) infection causes impairment of the gastrointestinal barrier, with substantial depletion of CD4<sup>+</sup> T cells in the gut. Antiretroviral therapy (ART) restores CD4<sup>+</sup> counts and may have beneficial effects on gut microbiota in adults. Little is known about effect of long-term ART on gut microbiome in HIV-infected children. We ...